By Choya Yoon, Mark H. Tuszynski (auth.), Rahul Jandial MD, PhD, Mike Y. Chen MD, PhD (eds.)
Editors desire that Regenerative Biology of the backbone and Spinal Cord appeals to the nostalgic sentiments of investigators and intellectuals in that it may be held in hand and supply a large survey of cutting edge technological know-how. while its chapters might be digitally got for these confirmed within the box to refine specific wisdom pursuits or gaps. most significantly, we ask the reader, whomever that could be, to peruse with out prejudice as numerous extra chapters can have been written sooner than overall spinal regeneration is achieved.
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Extra info for Regenerative Biology of the Spine and Spinal Cord
From a technical point of view, the mobilisation of endogenous stem cells avoids the problems associated with the use of embryonic and non-embryonic stem cells, the possibility of graft rejection and uncontrolled graft cell proliferation and tumour formation. HYDROGEL AS A TISSUE REPAIR PROMOTER AND A NICHE FOR THE RECRUITMENT OF MIGRATING ENDOGENOUS NSCs Hydrogels form a three-dimensional network ofcross-linked hydrophilic polymers that can take up large volumes of water or organic fluid after transplantation while retaining the three-dimensional geometry of the macromolecular backbone.
Neuroscience 2006; 143:501-514. 118. Zou H, Ho C, Wong K et al. Axotomy-induced Smadl activation promotes axonal growth in adult sensory neurons. JNeurosci2009; 29:7116-7123. 119. Seijffers R, Mills CD, WoolfCJ. ATF3 increases the intrinsic growth state ofDRG neurons to enhance peripheral nerve regeneration. J Neurosci 2007; 27:7911-7920. 120. Bomze HM, Bulsara KR, Iskandar BJ et al. Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons. Nat Neurosci 2001; 4:38-43.
121. Lachyankar MB, Sultana N, SchonhoffCM et al. A role for nuclear PTEN in neuronal differentiation. J Neurosci 2000; 20: 1404-1413. 122. I, Brooks Al et al. Inhibition of neuronal phenotype by PTEN in PCI2 cells. Proc Nat! Acad Sci USA 2004; 101:3627-3631. 123. Chadborn NH, Ahmed AI, Holt MR et al. PTEN couples Sema3A signalling to growth cone collapse. J Cell Sci 2006; 119:951-957. 124. Park KK, Liu K, Hu Y et al. Promoting axon regeneration in the adult CNS by modulation of the PTENI mTOR pathway.